Trail of Cthulhu is a new GUMSHOE system game under license to Chaosium, set in the 1930s released 1st March 2008.
It supports both Pulp (for Indiana Jones, Robert E. Howard, thrilling locations sorts of games) and Purist styles of play(for intellectual horror and cosmic dread). HP Lovecraft's work combined both, sometimes in the same story.
It includes a new take on the creatures, cults and gods of the Lovecraft's literature, and addresses their use in gaming. It adds new player backgrounds, and bulk out the GUMSHOE system to give intensive support for sanity, incorporating into the rule set the PCs desire to explore at the risk of going mad.